REJURAN VARIANTS EXPLAINED: HEALER, I, S, HB, EYE IN SEOUL

Rejuran is not one product. It is a family of polynucleotide injectables, and each version was formulated for a specific tissue depth, a specific concern, and a specific price bracket. Walk into a Gangnam clinic asking for "Rejuran" without knowing which one, and you are handing the coordinator a blank cheque to upsell whichever variant has the fattest margin that week.

Seoul clinics stock five common versions of the line: Healer, I (Injector), S (Scar), HB (Hyaluronic Booster), and Eye. They share the same salmon-DNA backbone, but the molecular size, concentration, and needle protocol change enough that booking the wrong one is a common way first-time visitors waste four hundred US dollars. This guide breaks down what each variant actually does, what a session runs in KRW and USD as of 2026, and which one to start with if this is your first trip. For the deeper procedural walk-through of the flagship product, see the Rejuran Healer full guide.

WHAT EVERY REJURAN ACTUALLY IS

All Rejuran variants are polynucleotides, or PN, extracted from purified salmon sperm DNA. The fragments are short chains of nucleotides that, once injected into the dermis, do two things at once. They act as a physical scaffold that holds water and supports fibroblasts, and they signal repair pathways that push collagen and elastin synthesis. This is different from a hyaluronic acid filler, which sits in the tissue and adds volume, and different from a neurotoxin like Botox, which relaxes muscle. Rejuran rebuilds the skin itself.

Because it is a repair signal rather than a volumiser, results build over weeks, not days. A standard protocol in Seoul is three sessions spaced two to four weeks apart, then a maintenance session every four to six months. Downtime is minor, usually two to three days of small bumps at the injection sites. The differences between the five product versions come down to molecular weight, concentration, and what the manufacturer paired the PN with. That is where the pricing splits.

For a broader look at how PN sits against the other collagen-building category, the Rejuran vs skin boosters comparison is the useful next read.

REJURAN HEALER: THE DEFAULT FOR OVERALL SKIN QUALITY

Healer is the original PharmaResearch product and the version most clinics quote when a coordinator says "Rejuran" without a qualifier. It uses a medium-density polynucleotide fragment concentration and is designed for full-face injection at a moderate depth. The target is overall skin quality: fine lines, dullness, thin post-acne skin, early laxity, and the papery texture that shows up in the mid thirties. It is what most first-time Rejuran patients in Seoul actually book.

A single Healer session in Gangnam or Sinnonhyeon runs around 250,000 to 380,000 KRW, roughly 180 to 275 US dollars before VAT. Package pricing for three sessions typically lands at 700,000 to 1,000,000 KRW, about 505 to 725 US dollars. Clinics in Cheongdam quote higher, often 450,000 KRW per session, and the price gap does not always reflect a better product. It usually reflects the neighbourhood and the doctor's name on the door.

Healer is the correct pick if you cannot articulate a single hyperspecific concern. "My skin looks tired" is a Healer answer. Booking Healer as your first Rejuran session and evaluating after the third visit is the low-regret path. If you want to see what a first-time appointment actually looks like end to end, the first-time Rejuran walkthrough covers the arrival, the numbing wait, the injection pattern, and the immediate aftercare.

REJURAN I AND S: FINE-TIP AND SCAR-DENSITY VARIANTS

Rejuran I, sometimes marketed as Rejuran Injector, uses a thinner formulation and a smaller-gauge needle. Clinics use it for delicate zones where standard Healer would be too dense or too traumatic: the perioral area, the fine crepe skin around the mouth, thin forehead skin, and the transition zone into the temples. It is not a stronger product. It is a more precise one. A session usually runs 10 to 20 percent above Healer for the same coverage area, and clinics often bundle it into a Healer plan for the trickier zones rather than selling it as a standalone.

Rejuran S is the scar-density variant. It carries a higher concentration of polynucleotide fragments and is designed to be injected directly under atrophic acne scars, ice-pick pits, and depressed post-surgical scars. Clinics in Seoul price S higher, often 350,000 to 500,000 KRW per session for a targeted zone rather than a full face, and the protocol usually stretches to four or five sessions because scar remodelling takes longer than a general glow-up. If your primary reason for coming to Korea is acne scarring, S combined with a device like an ablative laser or RF microneedling is a stronger stack than Healer alone.

REJURAN HB: THE HYBRID WITH HYALURONIC ACID

HB stands for Hyaluronic Booster. It blends the standard polynucleotide fragments with a low-crosslink hyaluronic acid, so the syringe delivers both a repair signal and an immediate hydration payload. The visible effect is faster than pure Healer. Patients see plumpness and glow within about a week, which is why HB is the version most often recommended for a compressed trip where you want a visible before-and-after inside a ten-day stay.

Sessions run around 350,000 to 450,000 KRW in Gangnam, roughly 250 to 325 US dollars before VAT. HB is not a replacement for a filler where you actually need volume. It is a skin-quality treatment that borrows the immediate look of a hydration booster. If you have both texture concerns and a hard deadline like a wedding photoshoot, HB earns its higher price. If you have six months of maintenance ahead of you and no fixed event, standard Healer is more cost-efficient over a year.

One practical note. Because HB contains HA, patients on blood thinners or with active facial inflammation have slightly more bruising risk than with pure Healer. Disclose everything in the consultation, and if the doctor waves it off without asking about anticoagulants or aspirin use, that is a signal about the clinic, not about the product.

REJURAN EYE: WHAT THE TEAR TROUGH VERSION ACTUALLY DOES

Rejuran Eye uses a smaller molecular weight fragment designed for the extremely thin skin under the eye. It does not fill the tear trough the way a hyaluronic acid filler does. It thickens and improves the skin quality of the lower lid, softens fine lines, reduces the crepe texture that shows up in flash photos, and gently pulls the whole under-eye zone toward looking rested rather than hollow. If your under-eye issue is thin, papery skin over a still-decent fat pad, Eye is the right tool. If your issue is a visible hollow with a shadow, Eye alone will disappoint you.

Pricing is tighter because the treated area is small. Expect 180,000 to 280,000 KRW per session, roughly 130 to 205 US dollars, and a three-session baseline. Cheongdam clinics anchor the top of that range. The nuance of when to pick Eye versus a filler in the same anatomical zone is covered properly in under-eye hollows: filler vs Rejuran Eye, and the short answer is that they solve different problems and are frequently combined rather than substituted.

SO WHICH VARIANT SHOULD YOU BOOK FIRST?

For most first-time visitors, the honest answer is Healer, three sessions, in a Sinnonhyeon or Gangnam clinic in the 280,000 KRW range per session. That gives you a real read on how your skin responds to polynucleotides before you spend more on Eye, HB, or S. Book the specialised versions only when you have a specific concern that matches what the variant was formulated for.

• 01Overall dullness and thin-skin quality, no specific concern: Healer, 3 sessions, budget 280,000 KRW per session.
• 02Fine crepe skin around mouth or forehead: Healer plan with I added for the delicate zones.
• 03Atrophic acne scars as the main reason for the trip: S, 4-5 sessions, plan to combine with RF microneedling or fractional laser.
• 04Fixed event deadline inside 10-14 days: HB for the fastest visible glow, budget 400,000 KRW per session.
• 05Crepe under-eye skin with intact fat pad: Eye, 3 sessions. Add filler only if a hollow is also present.

The upsell trap to watch for is a coordinator who pushes you toward the most expensive combination on your first visit. A doctor who genuinely evaluates your skin will often start you on Healer and add complexity later if the response is uneven. For the full pricing breakdown across the line, the Rejuran cost breakdown has the current 2026 numbers per session, per package, and per clinic tier.

“Book the specialised versions only when you have a specific concern that matches what the variant was formulated for.”

FAQ.

Pricing ranges reflect typical premium SeoulClinics partners and are indicative — actual quotes come from the consult. None of this replaces a licensed Korean clinician's evaluation.